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Consistent with a protective effect of vitamin therapy, higher plasma homocysteine levels were associated with an increased risk of new cardiovascular events in normohomocysteinemic but not in vitamin-treated hyperhomocysteinemic subjects

Supplemental creatine may reduce the need to manufacture creatine from SAM, conserving methyl groups and reducing SAH generation from endogenous creatine synthesis

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Sikiric, P., Hrelec, M., Knezevic, M., et al

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Gastrointestinal glutathione peroxidase prevents transport of lipid hydroperoxides in CaCo-2 cells